Desenvolvimento e caracterização de membranas de poli (- caprolactona) eletrofiadas e modificadas com extrato de Libidibia ferrea L. e acetato de celulose para aplicação na Odontologia

Abstract

The search for materials composed of natural products and developed as delivery vehicles for bioactive compounds with properties and characteristics suitable for partial or total repair of human biological tissues has been extensively studied in recent years. Libidibia ferrea extract has several properties, including antimicrobial, anti-inflammatory, and wound healing. This study aimed to develop and characterize membranes using polycaprolactone (PCL) and modified with Libidibia ferrea L. (Jucá) extract and cellulose acetate (CA) for dental application. The membranes were characterized through morphological, physicochemical, and bioactive release analyses. The results indicated that the incorporation of the extract promoted modifications in the surface and structural characteristics of the membranes. It can be concluded that the membranes produced in this study showed promising potential for application as controlled drug delivery devices in the oral cavity.